Intensity Modulated Beam Radiation Therapy Dose Optimization with Multiobjective Evolutionary Algorithms
نویسندگان
چکیده
We apply the NSGA-II algorithm and its controlled elitist version NSGA-IIc for the intensity modulated beam radiotherapy dose optimization problem. We compare the performance of the algorithms with objectives for which deterministic optimization methods provide global optimal solutions. The number of parameters to be optimized can be up to a few thousands and the number of objectives varies from 3 to 6. We compare the results with and without supporting solutions. Optimization with constraints for the target dose variance value provides clinical acceptable solutions.
منابع مشابه
Direct Aperture Optimization for Intensity Modulated Radiation Therapy: Two Calibrated Metaheuristics and Liver Cancer Case Study
Integrated treatment planning for cancer patients has high importance in intensity modulated radiation therapy (IMRT). Direct aperture optimization (DAO) is one of the prominent approaches used in recent years to attain this goal. Considering a set of beam directions, DAO is an integrated approach to optimize the intensity and leaf position of apertures in each direction. In this paper, first, ...
متن کاملIterative Approach for Automatic Beam Angle Selection in Intensity Modulated Radiation Therapy Planning
Introduction: Beam-angle optimization (BAO) is a computationally intensive problem for a number of reasons. First, the search space of the solutions is huge, requiring enumeration of all possible beam orientation combinations. For example, when choosing 4 angles out of 36 candidate beam angles, C36 = 58905 possible combinations exist. Second, any change in a beam 4 config...
متن کاملMultiobjective Inverse Planning for External Beam Radiotherapy: Decoupling the Optimization and Decision Processes
Inverse planning in radiation therapy is a trial and error process and many studies have been published which consider different algorithms, constraints, cases and objective functions. These planning algorithms combine in a specific way the objectives that are in conflict but do not provide the information that is necessary to obtain an optimal solution. Only in the last few years have signific...
متن کاملIntensity modulated radiation therapy (IMRT) technique for left breast cancer by different numbers of beam fields
Background: Intensity Modulated Radiotherapy (IMRT) can improve radiotherapy (RT) results by improving healthy tissue sparing. Additionally, IMRT provides more consistent dose deliveries and suppresses secondary tumor formation. RT is a principal treatment in breast cancer (BC). Aim: To evaluate the outcome of the Radiotherapy Plans (RTP) that use IMRT technique to left breast and other organs,...
متن کامل3D-Conformal Radiation Therapy and Intensity-Modulated Radiation Therapy Techniques for Laryngeal Cancer Taking Parotid Glands as Organ at Risk
Background: Three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) techniques are used for the treatment of patients with laryngeal cancer. Objective: This study aimed to investigate the effects of these 2 treatment techniques on the planning target volume (PTV) (laryngeal cancer), dose homogeneity, dose of organs at...
متن کامل